when I was on prozac it made me even worse then i was before. after 3 months on it the doctor finaly took me off of it and said go do a special doctor. that when i was put on lexapro it did work, but my insurance never cover it so it cost me about $95.00 for 15 pills after that they put me on the sister drug and it did nothing for me, so now I have no doctor and have to use my own ways, that when i did some searching,and found out about st johns worth, I been on it for come to a year now and it works for me, but now my body is getting use to it so it nolonger working.
but the point is that you body is going to get use to every drug you take. everyone is different on how they react to each drug, just don't give up, find out what is causing your depression. If it is in your head then it could be a chemical inbalance, which means that your on the wrong type of drug, if it somthing outside doing it then therapy is your best bet.