I have lost my BR quite a few times, especially during my earlier years.
Luckily, I never deposited more than I could afford to play with (and potentially lose), so it never had a negative financial impact. Also, I only play micro-stakes MTTs, so I never deposited more than $25-$100 when I was starting.
I also look at playing MTTs as just a form of entertainment and nothing something I ever intended to grind, move up in stakes, and build a profit off of. Yes, I eventually did begin to profit off of microstakes MTTs after years of playing them, but that's just a bonus for me. But playing MTTs is just like going out and having a nice evening. I don't worry about spending, say, $40 for a decent dinner and a movie, and I probably did something like that multiple times a month. So, I don't worry about spending $100 for entertainment playing poker, except I try and make it last as long as possible and not spend it all on 1 game.