Heads up is a very unique situation, and I think that aggression plays its hole very well here, cause the odds for both sides really depends on the community cards. I watched a video of Daniel Negreanu heads up against his ex girlfriend, and the skill really made part of the game, not needed to mention he probably made her feel so bad playing that table. There are lot of guides telling you to play very loosely and play some mediocre hands, but be careful cause the same way that hand can lead you to win, it can also lead you to lose the first place (let's be ambicious and try to look for the best place haha). In my opinion, the flop will surely determine who is probably the winner of one hand, although there are other 2 cards to come, if someone doesnt hit the flop and gets bet, he'll probably fold it even if it was KQ on a flop like T66, cause even if the bet from the other player could be a bluff, it's not worth to put more money into it.
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