Of course you fold it sometimes preflop, Ill give you a good senario.
Villan is a conservative player, and just limps, you bet with ur AK, someone else
raises your bet, and villan raises again! I mean come on. There is no chance villan would do that with AQ or A anything, probably not even with AK. So what could he have. Well if he has like JJ or QQ ur still losing! and if the has AA or KK your wayyy behind. So in this case... i mean there is a good chance that your far behind and especially considering the fact that he did a check raise!!! These things you have to consider, and you know its not a
bluff cause he would be
bluffing 2 people out of the hand that both placed a bet/raise... very unlikely for a conservative player to do that... so do the math.