Don't. Only -- sometimes-- play them from late position, in an unraised pot. And raise with them. On the flop, if it's checked to you, c-bet.
You want to flop a set. That's pretty much it. Any resistance at the table, they have to be folded. Basically, they are crap that can be beat by any other playable hand that hits at all.
You will see a lot of people who get lucky with them, shoving allin on the flop and they hold up. But that's like getting lucky with ATC. It's fun for you when it happens to work out, but you look like a dope the many other times when it doesn't.