Certainly, the professionals recommend having at least one day of rest during the week. Whenever I do not play for several days, I get better results when I get back.
One of the things I see happening a lot is you bet with wrong hands. Sometimes a sequence of bad hands comes to you and if you are stressed, you will probably play with the next hand without caring, because you are already stressed. It happened a lot with me, for example, getting 20 hands in a row with bad cards coming in my hand, that's desperate hahaha
ALWAYS take breaks. Especially if you're running bad.