early position if the blinds are low try limping in or getting to see a flop for super cheap to set mine your low pairs, hit your set great if not check/fold most boards.
late position with low pairs do a standard raise + c-bet, if you're called then possibly slow down unless you have a good read on them.
if you get re-raised pre-flop then re-evaluate based on your odds
, both immediate + implied odds and your reads before deciding whether to call or not.
middle + late stage of a game i tend to fold certain small pairs in early position since most of the time there will be a better hand further down the table which you wont come up against and you really wont want to go all in with a low pocket pair from early position unless you are super short.
having said all that if i was a monster chip stack i'd play any pair from any position!
that's just my opinion on low pairs, im not a great player or anything but im sure other people will have their own ideas on how to play low-medium pockets more profitably.
hope this helps you in some way