It really depends on the stake we are talking about, but going to the basic, that means, to the small stakes, the best strategy that can profits most from it is the ABC poker , which is playing the Tight Aggressive style, so, playing few hands and once you enter in a pot, you play it to win, you play it aggressively, especially when you've got position on the table.
Well, that's what most of the book's writers tell us, but we can't say that playing loosely won't bring you some money, surely will, but it's harder to play Loose Aggressive, cause you need to know how to fold a hand in some hard spots, even those that you have already put a lot of money on the felts.