2/1 ratio is when you use a standard size. Depends on your size. If you use huge size for raise, then you can add more bluff. Like the overbet. The overbet have more bluff than 2/1 if this bet is "balanced".
Like as said, look the spots from "his eyes". And you will understand. See with which
hands he can call profitably.
And you can raise more IP. Because you can add for bluff some hands, which you can't call, but you have some outs, some equity. You can check back. This not be always, he can 3bet, he can donk OTT. But still you can use more raise IP, than check-raise. But raise postflop isn't a standard move, you ranges for call becomes weaker. And you are talking for balance. It is not so simple. What's why GTO is more "easy" with two ranges, not with three. I mean you have range for fold, range for call. You must take some hands from your range for call. For value raise. And then becomes more difficult to balance your range for call. It is not a good move, you know. The bluff raise. I use that only bluff heavy ot value heavy. Mainly 100% bluff, 100% value (exploit). But if we talk about this, in which spots is the best the balance, then, yes, this are the best spots. Check-raise. If you are talking about micro limits. Because very rare you will know how the people will react against this. You will have some assumptions, but rarely you will be sure. But again, it is better to use "value heavy" balance or "bluff heavy" balance (not "perfect" balance). You can't use GTO for microlimits. I mean a "perfect" balance. GTO still will "win" some money at the microlimits, because the people are overaggro this days. But there is a better way. Exploit...
I will try to explain this more simple. If you expect more FE, then use more bluffs. Like 50/50 ratio. But be carefull for the value raise. Must be only very strong hands. If you expect less fold equity, then use more value hands. Very rare a bluff. let's say 25%...And you can add weaker hands for raise. Like two pairs. Depends on this vs which position you raise, how wide is his range for open raise (3bet) and his calling range vs raise. That's it. When you have more experience, you will use some solvers, and you can use some balance. Perfect or not. But if you understand this, you can do that very easy without software. This is just a tool. "Help"...Not a "teacher",a "coach"...
And ofc you can add more bluffs, if there are some outs. If there are many outs, more bluff then. Also if the draws are pretty strong. With overcards, Axs FD, hands with showdown value...
Also don't forget about the rake. If you play at micro big pots very often, this is not very good, you know. It is better when the rake "have" a cap.