Mixing up your game should be something every player should be implementing into their strategy - but let's not overthink this too much.
For myself, I switch between TAG, LAG, and LP (loose passive). I do not deviate from normal bet sizing - it turns your hand face up.
I play with a lady all the time in home games and say the blinds are 100/200 - she will open to 1200 - 1500 - sometimes even larger...this almost ALWAYS means she has a pocket pair, 99 or smaller and she doesnt want to go to a flop with overcards on it. I exploit this play from her ALLLLLL the time. Every once in a while she shows up with A9 or AJo but around 85% of the time or so it's a small - mid pocket pair.
So that being said - dont get carried away opening things like 99 or 10-10 from early position and making the raise oversized - when you do get called it's never going to be by
hands you are strongly ahead of. Two overs are only a 45% dog vs your 10s so it's really close to flip.
Anyhow - I'm staying off the subject. I mix things up by doing lots of things. If my stack is up there - I open hands from MP that I normally wouldn't - the LAG approach. Dont be afraid to 3 bet hands like A5s, QJs, J10s, etc - from late position. If you flop reasonably well I like to play them aggressively as if you may have an overpair. I like to do the same from time to time from the SB or BB. Calling to defend is just fine but sometimes 3 betting will allow you to win the pot outright without seeing a flop.
Another thing you can do is to check raise in spots where you normally wouldn't- I've check raised nothing but a gut shot and backdoor flush draw before simply because the flop represented my range better than my opponents. Playing your range moreso than your own cards can allow you to take down pots you normally couldn't win. Make sure you dont get carried away with your bluffs - but if you aren't mixing them into your game, you are not maximizing your profits. Keep in mind though - at the lowest of all stakes, less players fall for bluffs as they do not read into them as much. If you think you made a good bet with your
bluff attempt - be happy with your play, even when you get looked up.
Anyhow, lots of other information out there. I hope mine helps you in some way. Good luck to you