before the flop. a decent sized bet should get 2's - 7/8's to fold. You should look out for three bets, and hope you don't run into someone slow playing pocket kings or something (which you will inevitably run into)
Post flop, you should be cautious of 8's 9's and 10's, they often call a three bet without re-raising.
I don't however, think that you should alter your game heavily based on your experiences running into sets. Not everyone plays sets the same ways, it's impossible to know for sure what cards your opponent has. Often times you just have to hope you get lucky.
Good luck not running into sets
Have a good day