After I've been at the table a sufficient number of hands to identify a bluffer, I look for opportunities to exploit. It is very important, though, to not get caught up in the thought of "they're a bluffer, they're just throwing chips in" because EVERYONE gets good cards at some point. You must continue to pay attention to their play, changes in behavior, changes in bet sizing/bet patterns, etc. Otherwise, that bluffer could easily have you reloading or watching from the rail.