I've won a lot of hands with low pair but you really have to face them as if they were a hand that necessarily has to improve.
So you pay, as long as it's not too much, and try to complete the set or the straight.
Check the profile of the villains, if they are aggressive you may have to fold because they will increase a lot or because the flop will make your chips unviable.
Another situation is the end of the game, if villagers play a lot of AK AQ and you are running out of chips all in, it wouldn't be bad against a single opponent.