I defend the BB with KTo, i call the flop with 2 pair and a gutsot,hit the strait t and stack myself(me and the vilain bouth had 300bb) wath coul go wrong?
https://www.cardschat.com/replayer/324tlGE9Q

He free rolled you - you got it all in with the nuts on the turn - what more can you do? This hand needs no review - you just lost a spot that you are going to chop most of the time. Nothing too be overly concerned about here...going broke with the nuts is ok.

You can also fold or 3bet (mostly fold) KTo from the BB here. Flatting KTo OOP vs a MP PFR I think is tough to be profitable. If we make a pair we still aren't always good and being OOP always makes it harder to realize equity. There will be tons of spots on the flop like this where we flop a piece and call another bet only to miss and lose more.

Would you be able to fold if it came to the river ? In my opinion, this is not easy to do.

In this case you are playing with a deep stack (300bb) for which you can better provide your betting sizes, taking into account that the villain you face also has a condition similar to yours.
On the turn, you must ask yourself what hands of rank v, can make 4bet from co on a high structuring board.
If we think of the range of the villain, we can polarize basically 2 types of hands: sets or combo flush draw.
It should also be noted that the fact that we block the main straight, does not mean that it is not possible for CO to have a T in its range. In fact villain has 9 free A-T combos, which could perfectly be included in its CO range.
Besides, since we don't have a clover blocker, we can think of the idea that this villain is probably willing to look for all his positive equity at this point. This is one reason, to protect our calling range to a 4bet of CO position.
An 5bet from us, automatically commit the stack v to the pot that is played. The same thing happens with our stack. On the other hand, the call to 4bet of the turn, allows us a greater margin of playability in the river, to make better decisions, with a greater degree of analysis.
In that case on the river, the Q is bent and the flush line is completed.
Now we lost whith A-A (3 combos) J-J (3 combos) K-K (1 combo) Q-Q (1 combo) and clover combos . Our hand can now become in a bluff catcher and maybe we will be defeated many times with better hands, but our line will probably have less negative impact, since we will only protect our range of calls, without creating alternatives of out of position attacks.
Greetings.

I think you had bad luck on the river but maybe you could lose less money in this hand on the turn with the Q after the check raise of yours and the raise of the villain you were playing for the rake it was quite obvious that both were 10 so I would have called only his raise and then I would see what the villain was going to do with his flush if he was going to go all-in it was very difficult for you to fold that hand but maybe that would not have been the movement of the villain and you would have saved a couple of dollars in that hand

For me the problem is preflop. 300bb deep I would just muck KTo vs MP unless he opens way too wide. Being OOP with so much money behind with a hand that is so often dominated is quite risky. The best you can get is a king high street. All other hands are tricky as broadways are very much in his range too.

I don’t mind getting it in on the turn but getting it in for a chop is usually not ideal with 300bb in case of draws out there. If we think he can get 300bb in on a four straight board with two pair or set than this makes it better. But I would expect someone to see the river after your raise and try to boat up.

Its OK to call with KTo in BB (fold in all ather positions). -100 BB/100 its a lot.

300bb deep it's not ok to call with KTo, because it is super dominated by AK, KQ, AT, KK, TT. A lot of times you will hit top pair and lose a huge pot.

It is majority fold even 100bb deep, especially at low stakes where rake is very high. OP's only mistake is preflop.

Pre flop I'm not a fan of the call. I don't like calling with off suit Broadway cards. Flop, still not a fan. You're basically just gambling with no guarantee of getting paid if you hit. If your going to gamble, I think raising is better. Folding was best. Once you hit your fine getting it all in. .. You see the value of being suited.

Yes i think playing 300BB deep, you better have hands with more nut potentials to avoid freerolling situation

I never make cash outs because it's killing authenticity of poker also it doen't give math advantage.
What about hand preflop and flop you played well. What about turn best for you had the equality. For such huge stacks all in is bad idea )