i think preflop reading can also help make the best decision post flop...
you have a decent read on your opponant you know his range of hands include any pair, and he limps in from early position, youve seen him limp in before, but never with Ace king type hands. you get ak suited so you make the raise in position, getting the blinds out of the way and getting heads up in position against your opponant... flop comes A 2 7, seemingly good flop for you, but its not a hand that i would go all in with if me and my opponant were deep stacked.. he checks, i would probably check here sometimes, but lets say you bet and he check raises you, well, he COULD be bluffing
he COULD be representing an ace, but its also likely he has hit that exact hand, trip 2s or 7s..
what im getting at is this, you need to constantly be observing what your opponant is doing at the table (this is the main reason i will not ever multitable more than 2 tables).
oh and believe me, your opponants are not bluffing nearly as much as you might think they do.. and if you are getting bluffed off hands like this, in my opinion you are playing well.. even though in this instance he raised with 10 10. your ace was well ahead.
I remember daniel negreanu playing a hand on youtube i think i saw it.. he had pocket 9s, i think he raised and got one call from a guy in position and a guy in the bb, the flop comes 4 6 8 or something all low cards, the guy in the bb makes a stab bet at the pot and negreanu raises with his 9s, the guy in position just calls.. he looks a bit perplexed and the turn comes down dunno what card maybe a jack. negrenu checks and the player takes a while and just checks, negreanu knew something was up, his 99 didnt look so good now, he knew exactly what that particular player had i mean the gig was up, he might as well have just raised the flop. daniel checks the river and the player bets out a pot sized bet, hoping that it would seem bluffy, he says" so you got pocket 4s or pocket 6s, which one?" should see the look on that guys face hahaha