It really depends on the format and the players at my table. I would almost always go for a 4-bet, unless i have information that the player is VERY tight. Once you get 5-bet it is player depending for me, and i would usualy take more risk in re-entry and rebuy tournaments because i think other players will take more risk in those formats. In a 6-max game i'd probably get it in anyway, in low stakes games because i think they simply play to aggresive and overplay hands and its not capped to KK+. Though, in a softer field it would suck to get it in early, for a flip and possible behind. Usualy they won't go to out of line with hands like AQ that you dominate. Getting it in, or calling the raise would all depend about how deep we are, and howmuch i would have behind calling the 5-bet. In games i play recently i would probably go for a call, with a 50K monster stack assuming the 5-bet would be to around 7K unless i have previous information that this player spews chips and is overly aggresive, then i'm willing to take the risk to 6-bet get it in and if he has it then oh well.