With so little info in the OP, we have to speak in generalities. Against 2 big agro stacks, I'm gonna flat here and re-evaluate the flop. If those big stacks have NOT been agro, I would do a table standard raise or re-raise, whatever that has been.
My willingness factor is high in both cases...meaning I am willing to get it all in, but since I know that they probably know, I am going for chip accumulation rather than trying to close down a hand early. This can backfire, obviously, and it does seem to often.
With these hands, IMHO, position is much less important.