I really like rlingn's answer.
Each and every hand is different, depending on your stack, your position and how the rest of the table is (has been) playing.
The really good players know when to attack, when to lay back and when to re-adjust their game accordingly.
I think that a lot of the multi-tablers (8-16-24 at a time)
don't get this.
They are playing the odds
that they will profit on at least 40-50% of their tables and that is considered a good day.
I prefer to play a one or a few tables and pay attention to the decision at each one, so I can make the right decision (doesn't always work lol)
Just my ¢