The simplest answer is using an OTE strategy, which in term is unexploitable, players that sway away from OTE will become exploitable to us,
this is simple against bad players but as you move up it becomes more of a deadlock in my oppinion the best way to keep on top at the higher stakes is to constantly think about your image,
for example if people work out how solid we are playing, we make certain adjustments knowing that they are putting us on the OTE range this can allow us to capitalise on some big pots when we flop a speculative hand or a low hand.
Also these OTE regs will consistantly fold in spots where they know most of the time this is not a bluff,
they dont care if we are bluffing
since the profitable play is to fold long term,
so the more convincing our play the better success we will have
essentially though as the new breed are coming through we need to be creative ourselves and be good enough to come up with our own tactics