Every time you choose a hand to play you need to make a plan. Generally we will use suited cards with the possibility to win until without a flush, like a top pair, two pair or straight...
Generally we will not play all the suited card, we prefer to play ATs+, Suited connectors, playing suited cards with a low kicker we can make a flush, but there are possibilities to any other player have a flush with a better kick.
In each position you need to play with caution, try to avoid get involved in multway pot, you can use your image to bluff, floating, making check/raise, over bet, but in the most of case you need fold your unmade hand.