Depends on if they are lose, or if they are tight.
Tight/passive players should be bluffed a lot, and folded to once they raise.
Lose/passive players are easy to play. Just wait for a hand, and take them to valuetown. And just check it down if you havent hit.
Against lose/agressive players you need to be patient, and wait until you have a nice hand.
Tight/agressive players are often the most difficult to get value against. Just try to figure out their play, and stay one step ahead of them.
There really are a bunch of different player types, and giving one universal advice would be like telling u to always chose rock in rock, paper, scissors, but if you play vs beginners you should usally try to play a simple, straight forward game.