From a GTO standpoint, your opening raise size should increase the closer you get to the button. If it were graphed, I'd imagine it'd either look like half of a hyperbola, or a bell curve. Whether the difference in size between UTG and the button is even large enough to make any sort of difference, I don't know.
Obviously, from a more practical view, generally you do want to play smaller pots OOP and larger ones in position. This doesnt, however, directly relate to opening raise sizes. A smaller raise may actually lead to a larger pot by getting multiple callers and/or encouraging 3-bets.
It's definitely a complex issue, with many strong and weak points on either side.