I'd say it all depends on the players your playing against...Playing ATC vs passive players has it's merits, and playing A/x vs weak/passive players has its ups and downs..
As already stated A/Rag is a bothersome hand vs alot of players, but it can be profitable vs weak/passive players...Yet shut it down if you get called on the flop (unless you feel you can take them off've it)..
Again same rules apply with 3 betting what type of player are you 3 betting? How many players are in the hand when your 3 betting, what's your position on the table when 3 betting? How often are you 3 betting the original raiser, and what's your image on this table to these players in the hand/left to act of you? Are these players your 3 betting passive/calling station are they the type that (I have a piece and I'm not folding for nothing, irregardless of all the bets that are taking place)? All these things you'd have to consider before making anything vs anyone at any-time..
But in general it's just better to muck A/x pre just so you don't really get yourself into an ugly situation