You don't really want to mess with the regs, especially OOP. IP/from the blinds I'd 3-bet them light here and there with Axs/KQo/KJs if they have a high fold vs 3-bet and a high steal %. I defend my BB a little wider if they min-raise/2.5x the BTN/CO. But other than that I'm leaving them alone. I make a lot more money off the fish.
If they are 3-betting you light, then you should tighten up from the SB. He has positional advantage over you, and he's probably going to be calling pretty wide and outplaying you postflop. Or 3-betting you quite often, and making you fold preflop.
I think "teaching" someone that they can't mess around with you, especially on Zone and against a maniac, is sort of immature and spewy. If they are playing back at you too much, just find another table or wait until you have a strong hand and let them hang themselves. Since this was Zone, you could have just easily moved on.
Q10o is not a good open in Zone in the SB, as people defend their BB super wide in Zone, are more solid players than cash game players, and will play back at you pretty often with air preflop and postflop. 86o, 45s, Q high, etc. Play tighter from the SB on Zoom. Trust me on this one; I've played about 70-80k hands on Zone 25NL, 50NL, 100NL. In Zone my SB opening range is something like 15%, lower than my MP opening range and slightly above my UTG range. Once I tightened up from the SB in Zone, my winrate went up a lot. People do not give credit to your c-bets in Zoom, and really they shouldn't. On J42, K105, K83, or A52 boards, most of your range can't withstand a bluff-raise or float.
As played, I think this is a really bad bluff. Although he is an aggro reg who 3-bets pretty lightly, I don't expect him to call your 4-bet with air and with the intention to bluff you in a 1 SPR pot. I also think the 4-bet bluff preflop is pretty spewy, as you block some 3-bet bluffs like Q10s, J10s, A10s, QJs, 109s, etc. Honestly I don't know what his calling range here is though. BvB I think a reg is getting in AK/KK/AA. He might flat QQ, and I don't ever see JJ flatting a 4-bet.