Originally Posted by Poker_play
AQs is well ahead of villain's range for small raise on button.
This is only one thing to consider, and one of the least important things to think about when you are 300 big blinds deep.
Preflop equity is almost meaningless when you're this deep. When you 3-bet to $50, the stack to pot ratio is 14:1. So even in a pot that started with a 5x open and a 3-bet, your opponent is getting enough implied odds
to set mine, draw at flushes and straights, ect. So getting committed with top pair is a hell of a bad idea.
3-betting larger is okay too, but I'd typically want a stronger hand than AQs.
So realize that when you 3-bet, you're also selecting the size pot that you want to play. And 300 deep, your 3-bet doesn't affect your opponent's implied odds (because he always has them). So I'd flat his raise, planning to play a small pot with top pairs. And whenever I flopped a gutshot or a lot of backdoor nut draws, then I'd look to semibluff check/raise flops like this.
Deep stacked poker is very different. Stick to playing 100 bb's deep if you can help it.