Also given his sizing I doubt I'm calling off 3streets even when I hit unless this guys a complete nutjob. Be much more wary on Kxx than Axx as you have 4x the combos of hands that beat you.
Some adjustments for if you cant move table:
If he flats alot of 4bets 4bet/fold for value.
If he doesn't have a 4bet flatting range start 4bet bluffing
If he is capable of 5bet bluffing 4bet stack QQ+/AK (this will be pretty rare).
If he is prepared to stack QQ and AK for 200bb 4bet/stack
If your have no firm reads on any of the above just flat and think hard preflop about whether he is capable of having anything other than KK+ when you hit your hand. (does AQ really pot the turn etc etc).