For me I think there is much merit in playing regional sites if you can find them.
Sites such as
Ladbrokes, or
william hill, or
gambling sites are made up of vastly regional players, or even
888 poker
Due to pokerstars and their extreme advertising and exposure anyone who is serious about poker unless they are an outside the box thinking person they are going to go for pokerstars and
full tilt poker (providing they have access to pokerstars)
for me being more unconventional in my strategy for profit I focus on specific games and specific sites, even if traffic is bad when the big tournaments and cash games do come around its pretty easy to just buy into the main tournament they have where the field is going to be soft as hell and unless I run into a cooler I can pretty much guarantee getting back at least my buy in at the very worst