Yours is a really broad based question. Would need a lot more details than you give here, and one specific answer couldn't possibly cover all the possibilities. On the surface it does look like you have developed a very specific table image / tells
Mix up your play a little. You did say you wait for that ONE 'reasonable' hand to play 'short-stacked'. Wondering why those all-inners 6 of 10 are winning. They are simply more aggressive, willing to put it all on the line, bet the farm, on that donkey hand. They know they have to start earlier to build that stack, or they too will be short-stacked making desperate moves. It's the risk they take, and it does bring rewards.
Learning how, when and where to pick that spot is a big part of it. Try some freerolls
and experiment. Don't let 100 hands pass you by.