I find it is always situational, meaning how is the table, but with being moved or having new players come randomly, you just have to take things as they come. My rule of thumb is, play position first and foremost, I always play my strong hands strait forward at the beginning, NEVER slowplay a monster in early stage. I am only aggresive with big hands, and if I limp small pp or sc I will usually bow down to a show of strength (unless I have a good read that
tells me otherwise). Like I said, situational, if I have a read, I will vary my play accordingly. But playing blind, I will be tight unless I have the nutz.