It's not a matter of comfort. I play higher limits than $200 frequently. It's a matter of "investing" to classify a player. Most players do not switch gears even though they know they should. They play the same cards and situations in the same way. I am willing to call more loosely to get some good notes on players. It will more than pay off later.
Let's say a draw situation is up and I think I am the favorite right now. I want to know if this guy likes to draw. If so, how much does it take to get him off a draw. I am not going to worry the least about blowing $100 at the start of a game to find this out. I may bet an amount that a good player would not call, but that a loose player might. I may take a beat on this hand but I know some valuable things.
Conversely, I may draw myself since I can only loose $100. Players typically classify other players only
in the very begining. So if someone sees me make some loose calls or other bad plays, they think I am like that all the time. That is fine with me! I can then change gears and get looser calls from them in the future. I can then represent a flush or a straight that hit when I think they do not have that beat.