Micros - position is EVERYTHING. Throw out the disconnected hands early on. Early you want double suited with high rankers, you want four way connectors or very close, or you want double pairs. Late position, you can be in the hand with almost anything, you can be raising pot sized pre-flop anything with drawing power or double paired.
Reason being, people call basically everything in PLO, which evens out everyone's equity. All the play is post-flop, and having position means you can make informed decisions.
Don't be a fish. Qualify your hands to the good shit early on. K7suited J 4 off is not a great hand. Playable from late position, but trash from early. Reason being, PLO has TERRIBLE reverse implied odds. So even though you may see your suit go by as the cards come out, that flush will bankrupt you when someone else has the A high flush or if the board pairs. You may think your missing prime flops but you may actually be saving loads of money by having folded your garbage.
Late position you can get loose with your raises. Here's why: you have position and everyone's calling, so with close to even equity you actually have the edge. If you raise a lot, people will start re-raising, and this is where pre-flop value starts to show up. AAKK is a GREAT hand - against one (maybe two) opponents. It's not really fantastic against more though. You want to get all your chips in against one opponent ideally with that kind of hand. Or you want position with hands like 789T where you can outplay one opponent.