I'm hard-pressed to come up with any flop where I'm not going broke with a set against just about anyone I've ever played, at least if stacks are around 100bbs.
Dakota and ChuckTs played a hand live versus one another in Vegas. The board was J-T-2 rainbow, Taylor (Chuck) had opened in middle position and Debi (Dakota) was the only one who saw a flop with him, and she was in position. Effective stacks were $600, and this was a 1/2 game. Taylor bets maybe $15 at the pot, and Debi raises to $50. He thinks for a little while, then he makes it $110. Debi thinks for a little while and raises again to $230 (I'm guessing at the bet sizes). Taylor looks like he's about to throw up. Knowing, as I did and as Taylor surely did, that Debi is a reasonably tight player, she will have a set there just about always. JT might have been an option when she raised the first time, but not when she raised again. Taylor's difficult decision means that he has pocket deuces. He thinks and thinks and finally calls. The turn is an ace, which I think Taylor decided completed the straight (in case Debi was getting seriously out of line with KQ) and he checks, Debi goes all-in and Taylor gets that pale god-this-sucks aura about him again. Finally he folds. Correctly.
But they were playing 300 deep, they were playing live, and they knew each other. 100bb deep, Taylor would have played for stacks without even blinking, even knowing Debi as well as he did.