This is very villain & game dependent. You cannot assume you are against a set every time but caution is in order. Stats, notes, the flow of the game, & live tells
would be my primary decision making tools. It would also matter if it is 6max or full ring. In any case it would be time to decide whether or not to go with the hand.
I am almost always getting it in in 6max. Full ring I would be more cautious.
Against an donkey who plays any ace or pair vs. a raise I would get it in.
Against a maniac I would generally get it in.
Against a weak tight player I would fold.
Against a calling station I would fold.
Against a solid player I would really have to think about it. If I thought he played straight forward I might call and check/ fold the turn. If he is tricky I would tend to raise/ fold. Being out of position really could make this a tough hand.