When I have a big stack, I open a little wider OTB/CO, a couple percent extra. I already open sort of wide so I can't add too many more hands. People are more likely to fold from the blinds (I believe, not sure) and they definitely 3-bet/play back post-flop wayyyy less. They'll usually play fit-or-fold on the flop. I also have position, which makes it harder for them to continue/make plays at the pot. But other than that not really. Opening wider just because you have a big stack from all positions like UTG/MP/SB is bad because you're going to usually or always be OOP. You need to have a better reason like fishies in the blinds.
But yeah, when you have a big stack, and i mean 500bb+, it's pretty fun. Nobody wants to play back, and they just hand you their money. Highest i ever got to was 980/990bb at 25NL a while ago. Couldn't reach 1000bb and stoppd after dropping to like 920ish.