Don't play while inebriated, you won't be at the top of your game, and will make mistakes. Also, do you use any form of BRM? I think $ 250 is a little bit on the light side for 10nl, but if you have a way to deposit more than your BR is technically bigger. It is 25 buy ins, and some people use 20BIs, so it's really up to you, but if you go on a big downswing I would def move to 5nl. 50BIs is more on the safe side, but not a concrete set in stone thing.
Try to stick with one type of game, like play ring games OR SnGs, but not both.
I would play 5nl if I were you and get a decent sample of hands in an see what your win rate is.
Just my 2cents, hope it helps some.