This, I think, depends on how your opponents play.
If you raise bigger in EP then you are raising more because of your increased hand strengtg in this position. However, the raise increase may be significant in terms of a percentage, maybe 1.5 times your LP raise, however in the context of BB and stacksize, its a small raise that really dosent generate much i the way of fold equity (there are few hands that LP will fold to a 5BB raise yet play with a 3BB raise)
Where not raising for fold equity where raising for value and to get the SPR down as much as possible.
You say it your self if some one is gonna call 3x there gonna call 5x so going for max value can never be to bad.
So essentially what you are doing is trying to create a bigger pot on average with your stronger hands in EP.
Yes, witch is awsome 
.
So the crux is how your opponents react to this. If they are aware (and they should be) that your EP range is very strong, then they should only be selecting hands that play well against this range. Therefore against a player who is somewhat positionally aware, you are creating a bigger pot, on average, against a player in position who is selecting hands based on your tight range.
The thing is that even if where playing against decent regs at micro/small stakes there never gonna be making some drastic adjustments because of a 2bb increase in our open raise imo.
If this where some higher stakes or table full of Ivey´s maybe things would be difrent, i dont know...
Further more the small increase in EP is quite likely to reduce the number of 3-bets you get preflop (something your range actually wants) and when you are 3-bet, on average, you should be up against a stronger range.
I kinda disagree with. Just because we change or raise slightly doesnt mean where gonna 3bet more or less.
When some one opens from UTG most players have a pretty set range there gonna 3bet with based on the opener i just dont think thats gonna change cause of a 2bb change.
So betting larger in EP (when everyone and his dog knows you have a strong range) dosent give you any advantage, all it does is to ensure you play a bigger pot out of position against opponents who know what your range is.
Good players are allways gonna know we have a strong range from UTG, fish dont have a clue, nothing changes imo.
And it does give us a advange, we get a lower SPR,gain more value and makes it easier to get stacks in.
Thats alot of advantages imo.
Against very loose players who are very aggressive and bluffly post flop, the larger raise size is good, provided you are happy to continue after they try firing one or 2 streets as a bluff.
Agreed
Against loose players who are very fit and fold post flop, the larger raise is also good as you are expecting them to fold to any c-bet unless you are bet (set miners) so again you are getting more money in preflop good and then taking it down with a c-bet.
Agreed
However, if your opponent is looking at your EP range and thinking 5% mmm I know what he has! and then playing accordingly its a bad strategy because he is selecting hands that play well and has position in a pot that has a lower SPR than had the PF bet been smaller.
1.If the SPR is lower that means where gonna be making smaller mistakes if we get it in bad postflop.
2.You seem to asume villain is never commiting postflop with a hand worse then our, thats just not the case.
Even if he is making changes to his range because of our strong range(witch he will do no matter if we open 3x or 5x) he is still gonna flop a good hand but worse then ours alot.
And if he does know our range is super strong he is also gonna be folding to our cbets alot of the 65% of the times he missed the flop.
So its certainly a valid stratagy but its one that works against certain player types and not others. It certainly snt something you should be doing 100% of the time in 100% of games because a thinking Button / CO is now able to play his position against you with a larger advantage (the lower SPR you will see by the turn)
