If you're on his right and he constantly re-raises you well you quite simply do not have the implied odds
to play a hand like that. You say everytime someone raised they re-raised. They then flat your raise and OOP alarm bells should be going off right away.
If the oppotunity arises take a seat to maniacs left.
When you say maniac are you talking about pre flop and post flop? If he is betting anything and stacking with nothing then leave him to hang himself if you flop a mosnter.
No need to CB as much if he just calls/re-raises.
Sorry forgot to answer the main question lol . Loosen up slightly but not too much. I'd loosen up abit more if I was to the left of the maniac. Obviously all this is table dependant on what the others players are doing and if they are loosening up, if they are stay fairly tight.