Hi - I'm not bragging, but heads-up or 3 - 4 person play is what I do best. Getting to the final table from the first table in an 18 person SNG is harder than winning the whole thing for me. LOL
When I'm heads-up, I don't play their game . . . I play mine. If I don't like my cards, I'll fold and give them the blinds and wait for a hand I want to play. Don't let them draw you into anything you don't want to play.
Also, even with a small stack - going all in may get you even. You'll even notice they won't go all in -- they guard those chips like gold. But only go all in when your hand warrants it. Also, come out betting big if you have a good hand. They will fold usually. Not always, but usually. Like others have said - it does depend, but I suggest you play your game, not theirs. Then if you do lose - you've played your game and should feel okay about it.