Obviously it is completely random, but like in my real time games I sometimes base the strength of my hand (pre-flop) on what happened last hand. I.E - If I saw trip 8's and I pick up an 8 I feel that there is a good chance of it popping up.
Now, in real time this works because a lot of the players I play with are quite possibly the most inept shufflers/dealers in the world, but online there is absolutely no justification for using it. But still I do.
Wouldn't recommend it though.