Really depends on positions for the most part and if this is cash games or tournaments and who's left to act behind. Also, 6max or FR?
For example, we can open any Ax in late positions vs really tight players. If we have really aggressive players who like to see flops, love to 3B pre flop etc then we should probably fold our worse Ax hands like A5o for example.
Also get out of the mindset of thinking Ax of the same suit is a hand you would rather get your chips in as opposed to TT. TT has Ax suited crushed.