www.holdemassistant.com offers a beta of their poker analysis and guidance tool. It works real time in a separate window that analyses your current hand and offers (among other things) pre-flop advice and, ranking of your hand against whats possible considering the open table cards and win odds
Holdemassistant doesnt support all sites, but the guy programming it is constantly adding to the field of supported poker rooms.
I am using this when i play Ladbrokes
and especially in the fast paced play on Bet365 it is proving very usefull (till i get annoyed about the tilt-style poker there and start making havoc).
The beta try out is free.